Kadmon Corporation, LLC – Product Pipeline Review

Global Markets Direct’s, ‘Kadmon Corporation, LLC – Product Pipeline Review – 2016’, provides an overview of the Kadmon Corporation, LLC’s pharmaceutical research and development focus.

The report provides comprehensive information on the therapeutics under development by Kadmon Corporation, LLC, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and the dormant and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note: Certain sections in the report may be removed or altered based on the availability and relevance of data.

Scope

The report provides a snapshot of the pipeline therapeutic landscape of Kadmon Corporation, LLC

The report provides overview of Kadmon Corporation, LLC including its business description, key facts, and locations and subsidiaries

The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities

The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages

The report assesses Kadmon Corporation, LLC’s pipeline therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type

The report features Kadmon Corporation, LLC’s out-licensed and partnered product portfolio and summarizes its dormant and discontinued projects

Reasons to buy

Evaluate Kadmon Corporation, LLC’s strategic position with total access to detailed information on its product pipeline

Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Identify and understand important and diverse types of therapeutics under development for Kadmon Corporation, LLC

Identify potential new clients or partners in the target demographic

Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics

Devise corrective measures for pipeline projects by understanding Kadmon Corporation, LLC’s pipeline depth and focus of pipeline therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Table of Contents

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Kadmon Corporation, LLC Snapshot 5

Kadmon Corporation, LLC Overview 5

Key Information 5

Key Facts 5

Kadmon Corporation, LLC - Research and Development Overview 6

Key Therapeutic Areas 6

Kadmon Corporation, LLC - Pipeline Review 9

Pipeline Products by Stage of Development 9

Pipeline Products - Monotherapy 10

Pipeline Products - Partnered Products 11

Partnered Products/Combination Treatment Modalities 12

Kadmon Corporation, LLC - Pipeline Products Glance 13

Kadmon Corporation, LLC - Late Stage Pipeline Products 13

Phase III Products/Combination Treatment Modalities 13

Kadmon Corporation, LLC - Clinical Stage Pipeline Products 14

Phase II Products/Combination Treatment Modalities 14

Phase I Products/Combination Treatment Modalities 15

Kadmon Corporation, LLC - Early Stage Pipeline Products 16

Preclinical Products/Combination Treatment Modalities 16

Discovery Products/Combination Treatment Modalities 17

Kadmon Corporation, LLC - Drug Profiles 18

trientine hydrochloride next generation 18

Product Description 18

Mechanism of Action 18

R&D Progress 18

KD-025 19

Product Description 19

Mechanism of Action 19

R&D Progress 19

KD-026 21

Product Description 21

Mechanism of Action 21

R&D Progress 21

tesevatinib tosylate 23

Product Description 23

Mechanism of Action 23

R&D Progress 23

Gene Therapy to Activate Aquaporin-1 for Xerostomia 25

Product Description 25

Mechanism of Action 25

R&D Progress 25

salirasib 26

Product Description 26

Mechanism of Action 26

R&D Progress 26

KD-033 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

KL-00148 29

Product Description 29

Mechanism of Action 29

R&D Progress 29

KL-00199 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

Monoclonal Antibodies to Inhibit PDL1 for Oncology 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

Monoclonal Antibody to Inhibit VEGFR-2 for Cancer 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

Small Molecules to Inhibit Acetyl-CoA Carboxylase for CMV Infections 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

Kadmon Corporation, LLC - Pipeline Analysis 34

Kadmon Corporation, LLC - Pipeline Products by Target 34

Kadmon Corporation, LLC - Pipeline Products by Route of Administration 36

Kadmon Corporation, LLC - Pipeline Products by Molecule Type 37

Kadmon Corporation, LLC - Pipeline Products by Mechanism of Action 38

Kadmon Corporation, LLC - Recent Pipeline Updates 39

Kadmon Corporation, LLC - Dormant Projects 44

Kadmon Corporation, LLC - Locations And Subsidiaries 45

Head Office 45

Other Locations & Subsidiaries 45

Appendix 46

Methodology 46

Coverage 46

Secondary Research 46

Primary Research 46

Expert Panel Validation 46

Contact Us 46

Disclaimer 47

List of Tables

List of Tables

Kadmon Corporation, LLC, Key Information 5

Kadmon Corporation, LLC, Key Facts 5

Kadmon Corporation, LLC – Pipeline by Indication, 2016 7

Kadmon Corporation, LLC – Pipeline by Stage of Development, 2016 9

Kadmon Corporation, LLC – Monotherapy Products in Pipeline, 2016 10

Kadmon Corporation, LLC – Partnered Products in Pipeline, 2016 11

Kadmon Corporation, LLC – Partnered Products/ Combination Treatment Modalities, 2016 12

Kadmon Corporation, LLC – Phase III, 2016 13

Kadmon Corporation, LLC – Phase II, 2016 14

Kadmon Corporation, LLC – Phase I, 2016 15

Kadmon Corporation, LLC – Preclinical, 2016 16

Kadmon Corporation, LLC – Discovery, 2016 17

Kadmon Corporation, LLC – Pipeline by Target, 2016 34

Kadmon Corporation, LLC – Pipeline by Route of Administration, 2016 36

Kadmon Corporation, LLC – Pipeline by Molecule Type, 2016 37

Kadmon Corporation, LLC – Pipeline Products by Mechanism of Action, 2016 38

Kadmon Corporation, LLC – Recent Pipeline Updates, 2016 39

Kadmon Corporation, LLC – Dormant Developmental Projects,2016 44

Kadmon Corporation, LLC, Other Locations 45

Kadmon Corporation, LLC, Subsidiaries 45

List of Figures

List of Figures

Kadmon Corporation, LLC – Pipeline by Top 10 Indication, 2016 7

Kadmon Corporation, LLC – Pipeline by Stage of Development, 2016 9

Kadmon Corporation, LLC – Monotherapy Products in Pipeline, 2016 10

Kadmon Corporation, LLC – Pipeline by Top 10 Target, 2016 34

Kadmon Corporation, LLC – Pipeline by Route of Administration, 2016 36

Kadmon Corporation, LLC – Pipeline by Molecule Type, 2016 37

Kadmon Corporation, LLC – Pipeline Products by Top 10 Mechanism of Action, 2016 38

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