AVEO Pharmaceuticals, Inc. – Product Pipeline Review

Global Markets Direct’s, ‘AVEO Pharmaceuticals, Inc. – Product Pipeline Review – 2016’, provides an overview of the AVEO Pharmaceuticals, Inc.’s pharmaceutical research and development focus.

The report provides comprehensive information on the therapeutics under development by AVEO Pharmaceuticals, Inc., complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and the dormant and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data.

Scope

The report provides a snapshot of the pipeline therapeutic landscape of AVEO Pharmaceuticals, Inc.

The report provides overview of AVEO Pharmaceuticals, Inc. including its business description, key facts, and locations and subsidiaries

The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities

The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages

The report assesses AVEO Pharmaceuticals, Inc.’s pipeline therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type

The report features AVEO Pharmaceuticals, Inc.’s out-licensed and partnered product portfolio and summarizes its dormant and discontinued projects

Reasons to buy

Evaluate AVEO Pharmaceuticals, Inc.’s strategic position with total access to detailed information on its product pipeline

Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Identify and understand important and diverse types of therapeutics under development for AVEO Pharmaceuticals, Inc.

Identify potential new clients or partners in the target demographic

Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics

Devise corrective measures for pipeline projects by understanding AVEO Pharmaceuticals, Inc.’s pipeline depth and focus of pipeline therapeutics

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Table of Contents

Table of Contents

Table of Contents 2

List of Tables 5

List of Figures 5

AVEO Pharmaceuticals, Inc. Snapshot 6

AVEO Pharmaceuticals, Inc. Overview 6

Key Information 6

Key Facts 6

AVEO Pharmaceuticals, Inc. - Research and Development Overview 7

Key Therapeutic Areas 7

AVEO Pharmaceuticals, Inc. - Pipeline Review 10

Pipeline Products by Stage of Development 10

Pipeline Products - Monotherapy 11

Pipeline Products - Partnered Products 12

Partnered Products/Combination Treatment Modalities 13

Pipeline Products - Out-Licensed Products 14

Out-Licensed Products/Combination Treatment Modalities 15

AVEO Pharmaceuticals, Inc. - Pipeline Products Glance 16

AVEO Pharmaceuticals, Inc. - Late Stage Pipeline Products 16

Phase III Products/Combination Treatment Modalities 16

AVEO Pharmaceuticals, Inc. - Clinical Stage Pipeline Products 17

Phase II Products/Combination Treatment Modalities 17

Phase I Products/Combination Treatment Modalities 18

AVEO Pharmaceuticals, Inc. - Early Stage Pipeline Products 19

Preclinical Products/Combination Treatment Modalities 19

Discovery Products/Combination Treatment Modalities 20

AVEO Pharmaceuticals, Inc. - Drug Profiles 21

tivozanib hydrochloride 21

Product Description 21

Mechanism of Action 21

R&D Progress 21

ficlatuzumab 25

Product Description 25

Mechanism of Action 25

R&D Progress 25

AV-203 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

AV-232 30

Product Description 30

Mechanism of Action 30

R&D Progress 30

AV-353 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

GP-369 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

AV-370 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

Monoclonal Antibody to Antagonize FGFR1 for Cancer 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

Monoclonal Antibody to Antagonize FGFR4 for Cancer 35

Product Description 35

Mechanism of Action 35

R&D Progress 35

Monoclonal Antibody to Target Notch2 for Cancer 36

Product Description 36

Mechanism of Action 36

R&D Progress 36

Monoclonal Antibody to Target Notch3 for Cancer 37

Product Description 37

Mechanism of Action 37

R&D Progress 37

Monoclonal Antibody to Target Notch4 for Cancer 38

Product Description 38

Mechanism of Action 38

R&D Progress 38

AVEO Pharmaceuticals, Inc. - Pipeline Analysis 39

AVEO Pharmaceuticals, Inc. - Pipeline Products by Target 39

AVEO Pharmaceuticals, Inc. - Pipeline Products by Route of Administration 41

AVEO Pharmaceuticals, Inc. - Pipeline Products by Molecule Type 42

AVEO Pharmaceuticals, Inc. - Pipeline Products by Mechanism of Action 43

AVEO Pharmaceuticals, Inc. - Recent Pipeline Updates 45

AVEO Pharmaceuticals, Inc. - Dormant Projects 54

AVEO Pharmaceuticals, Inc. - Discontinued Pipeline Products 55

Discontinued Pipeline Product Profiles 55

AV-412 55

tivozanib hydrochloride 55

AVEO Pharmaceuticals, Inc. - Company Statement 56

AVEO Pharmaceuticals, Inc. - Locations And Subsidiaries 60

Head Office 60

Other Locations & Subsidiaries 60

Appendix 61

Methodology 61

Coverage 61

Secondary Research 61

Primary Research 61

Expert Panel Validation 61

Contact Us 61

Disclaimer 62

List of Tables

List of Tables

AVEO Pharmaceuticals, Inc., Key Information 6

AVEO Pharmaceuticals, Inc., Key Facts 6

AVEO Pharmaceuticals, Inc. – Pipeline by Indication, 2016 8

AVEO Pharmaceuticals, Inc. – Pipeline by Stage of Development, 2016 10

AVEO Pharmaceuticals, Inc. – Monotherapy Products in Pipeline, 2016 11

AVEO Pharmaceuticals, Inc. – Partnered Products in Pipeline, 2016 12

AVEO Pharmaceuticals, Inc. – Partnered Products/ Combination Treatment Modalities, 2016 13

AVEO Pharmaceuticals, Inc. – Out-Licensed Products in Pipeline, 2016 14

AVEO Pharmaceuticals, Inc. – Out-Licensed Products/ Combination Treatment Modalities, 2016 15

AVEO Pharmaceuticals, Inc. – Phase III, 2016 16

AVEO Pharmaceuticals, Inc. – Phase II, 2016 17

AVEO Pharmaceuticals, Inc. – Phase I, 2016 18

AVEO Pharmaceuticals, Inc. – Preclinical, 2016 19

AVEO Pharmaceuticals, Inc. – Discovery, 2016 20

AVEO Pharmaceuticals, Inc. – Pipeline by Target, 2016 39

AVEO Pharmaceuticals, Inc. – Pipeline by Route of Administration, 2016 41

AVEO Pharmaceuticals, Inc. – Pipeline by Molecule Type, 2016 42

AVEO Pharmaceuticals, Inc. – Pipeline Products by Mechanism of Action, 2016 44

AVEO Pharmaceuticals, Inc. – Recent Pipeline Updates, 2016 45

AVEO Pharmaceuticals, Inc. – Dormant Developmental Projects,2016 54

AVEO Pharmaceuticals, Inc. – Discontinued Pipeline Products, 2016 55

AVEO Pharmaceuticals, Inc., Subsidiaries 60

List of Figures

List of Figures

AVEO Pharmaceuticals, Inc. – Pipeline by Top 10 Indication, 2016 8

AVEO Pharmaceuticals, Inc. – Pipeline by Stage of Development, 2016 10

AVEO Pharmaceuticals, Inc. – Monotherapy Products in Pipeline, 2016 11

AVEO Pharmaceuticals, Inc. – Partnered Products in Pipeline, 2016 12

AVEO Pharmaceuticals, Inc. – Pipeline by Top 10 Target, 2016 39

AVEO Pharmaceuticals, Inc. – Pipeline by Route of Administration, 2016 41

AVEO Pharmaceuticals, Inc. – Pipeline by Molecule Type, 2016 42

AVEO Pharmaceuticals, Inc. – Pipeline Products by Top 10 Mechanism of Action, 2016 43

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