Cathepsin S (CTSS or EC 3.4.22.27) – Pipeline Review, H2 2017

Global Markets Direct’s, ‘Cathepsin S (CTSS or EC 3.4.22.27) – Pipeline Review, H2 2017’, provides in depth analysis on Cathepsin S (CTSS or EC 3.4.22.27) targeted pipeline therapeutics. The report provides comprehensive information complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in Cathepsin S (CTSS or EC 3.4.22.27) targeted therapeutics development and features dormant and discontinued projects. The report analyses the pipeline products from therapy areas Central Nervous System, Immunology, Gastrointestinal, Oncology, Infectious Disease, Metabolic Disorders and Musculoskeletal Disorders under development targeting Cathepsin S (CTSS or EC 3.4.22.27).

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data.

*Updated report will be delivered in 48 hours of order confirmation.

Scope

The report provides a snapshot of the global therapeutic landscape for Cathepsin S (CTSS or EC 3.4.22.27)

The report reviews Cathepsin S (CTSS or EC 3.4.22.27) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources

The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages

The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in Cathepsin S (CTSS or EC 3.4.22.27) targeted therapeutics and enlists all their major and minor projects

The report assesses Cathepsin S (CTSS or EC 3.4.22.27) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type

The report summarizes all the dormant and discontinued pipeline projects

The report reviews latest news and deals related to Cathepsin S (CTSS or EC 3.4.22.27) targeted therapeutics

Reasons to buy

Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Identify and understand the targeted therapy areas and indications for Cathepsin S (CTSS or EC 3.4.22.27)

Identify the use of drugs for target identification and drug repurposing

Identify potential new clients or partners in the target demographic

Develop strategic initiatives by understanding the focus areas of leading companies

Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics

Devise corrective measures for pipeline projects by understanding Cathepsin S (CTSS or EC 3.4.22.27) development landscape

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Companies mentioned

Amura Holdings Ltd

F. Hoffmann-La Roche Ltd

Fusion Antibodies Ltd

Sanofi

Virobay Inc

Table of Contents

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Cathepsin S (CTSS or EC

3.4.22.27) - Overview 6

Cathepsin S (CTSS or EC

3.4.22.27) - Therapeutics Development 7

Products under Development by Stage of Development 7

Products under Development by Therapy Area 8

Products under Development by Indication 9

Products under Development by Companies 10

Cathepsin S (CTSS or EC

3.4.22.27) - Therapeutics Assessment 12

Assessment by Mechanism of Action 12

Assessment by Route of Administration 13

Assessment by Molecule Type 14

Cathepsin S (CTSS or EC

3.4.22.27) - Companies Involved in Therapeutics Development 16

Amura Holdings Ltd 16

F. Hoffmann-La Roche Ltd 16

Fusion Antibodies Ltd 16

Sanofi 17

Virobay Inc 17

Cathepsin S (CTSS or EC

3.4.22.27) - Drug Profiles 19

AM-3840 - Drug Profile 19

Product Description 19

Mechanism Of Action 19

R&D Progress 19

AM-3876 - Drug Profile 20

Product Description 20

Mechanism Of Action 20

R&D Progress 20

Fsn-0503h - Drug Profile 21

Product Description 21

Mechanism Of Action 21

R&D Progress 21

RG-7625 - Drug Profile 22

Product Description 22

Mechanism Of Action 22

R&D Progress 22

RO-5461111 - Drug Profile 23

Product Description 23

Mechanism Of Action 23

R&D Progress 23

SAR-114137 - Drug Profile 24

Product Description 24

Mechanism Of Action 24

R&D Progress 24

VBY-129 - Drug Profile 25

Product Description 25

Mechanism Of Action 25

R&D Progress 25

VBY-285 - Drug Profile 26

Product Description 26

Mechanism Of Action 26

R&D Progress 26

VBY-50365 - Drug Profile 27

Product Description 27

Mechanism Of Action 27

R&D Progress 27

VBY-825 - Drug Profile 28

Product Description 28

Mechanism Of Action 28

R&D Progress 28

Cathepsin S (CTSS or EC

3.4.22.27) - Dormant Products 29

Cathepsin S (CTSS or EC

3.4.22.27) - Discontinued Products 30

Cathepsin S (CTSS or EC

3.4.22.27) - Product Development Milestones 31

Featured News & Press Releases 31

Jul 27, 2015: NIH helps UC San Diego researchers repurpose Sanofi pain drug for tropical disease 31

Nov 14, 2014: Virobay To Present Data On Two Cathepsin S Inhibitor Programs In Neuropathic Pain And Alzheimer's Disease At The 2014 Society For Neuroscience Annual Meeting 31

Nov 14, 2011: Virobay's Spectrum-Selective Cathepsin Inhibitor Shows Efficacy In Bone Cancer Model 32

Appendix 33

Methodology 33

Coverage 33

Secondary Research 33

Primary Research 33

Expert Panel Validation 33

Contact Us 33

Disclaimer 34

List of Tables

List of Tables

Number of Products under Development by Stage of Development, H2 2017 7

Number of Products under Development by Therapy Areas, H2 2017 8

Number of Products under Development by Indication, H2 2017 9

Number of Products under Development by Companies, H2 2017 10

Products under Development by Companies, H2 2017 11

Number of Products by Stage and Mechanism of Actions, H2 2017 12

Number of Products by Stage and Route of Administration, H2 2017 13

Number of Products by Stage and Molecule Type, H2 2017 15

Pipeline by Amura Holdings Ltd, H2 2017 16

Pipeline by F. Hoffmann-La Roche Ltd, H2 2017 16

Pipeline by Fusion Antibodies Ltd, H2 2017 17

Pipeline by Sanofi, H2 2017 17

Pipeline by Virobay Inc, H2 2017 18

Dormant Projects, H2 2017 29

Discontinued Products, H2 2017 30

List of Figures

List of Figures

Number of Products under Development by Stage of Development, H2 2017 7

Number of Products under Development by Therapy Areas, H2 2017 8

Number of Products under Development by Top 10 Indications, H2 2017 9

Number of Products by Stage and Mechanism of Actions, H2 2017 12

Number of Products by Stage and Route of Administration, H2 2017 13

Number of Products by Molecule Types, H2 2017 14

Number of Products by Stage and Molecule Types, H2 2017 14

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