Dilated Cardiomyopathy – Drugs in Development, 2021

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Dilated Cardiomyopathy – Drugs in Development, 2021, provides an overview of the Dilated Cardiomyopathy (Cardiovascular) pipeline landscape.

Dilated cardiomyopathy (DCM) is a condition in which the heart's ability to pump blood is decreased because the heart's main pumping chamber, the left ventricle, is enlarged and weakened. Symptoms include Fatigue and weakness, Shortness of breath (dyspnea), lightheadedness, dizziness or fainting, persistent cough or wheezing, lack of appetite, sudden weight gain from fluid retention and swelling (edema) in legs, ankles and feet. Risk factors include family history, alcoholism, hypertension, cocaine abuse and metabolic disorders, such as thyroid disease or diabetes.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Dilated Cardiomyopathy – Drugs in Development, 2021, provides comprehensive information on the therapeutics under development for Dilated Cardiomyopathy (Cardiovascular), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Dilated Cardiomyopathy (Cardiovascular) pipeline guide also reviews of key players involved in therapeutic development for Dilated Cardiomyopathy and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, Preclinical and Discovery stages are 1, 4, 1, 6 and 3 respectively. Similarly, the Universities portfolio in Preclinical stages comprises 1 molecules, respectively.

Dilated Cardiomyopathy (Cardiovascular) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

– The pipeline guide provides a snapshot of the global therapeutic landscape of Dilated Cardiomyopathy (Cardiovascular).

– The pipeline guide reviews pipeline therapeutics for Dilated Cardiomyopathy (Cardiovascular) by companies and universities/research institutes based on information derived from company and industry-specific sources.

– The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.

– The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.

– The pipeline guide reviews key companies involved in Dilated Cardiomyopathy (Cardiovascular) therapeutics and enlists all their major and minor projects.

– The pipeline guide evaluates Dilated Cardiomyopathy (Cardiovascular) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.

– The pipeline guide encapsulates all the dormant and discontinued pipeline projects.

– The pipeline guide reviews latest news related to pipeline therapeutics for Dilated Cardiomyopathy (Cardiovascular)

Reasons to buy

- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.

- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.

- Find and recognize significant and varied types of therapeutics under development for Dilated Cardiomyopathy (Cardiovascular).

- Classify potential new clients or partners in the target demographic.

- Develop tactical initiatives by understanding the focus areas of leading companies.

- Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.

- Formulate corrective measures for pipeline projects by understanding Dilated Cardiomyopathy (Cardiovascular) pipeline depth and focus of Indication therapeutics.

- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.

- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Companies mentioned

Berlin Cures Holding AG

Bristol-Myers Squibb Co

Celixir Ltd

CellServe GmbH

Dynomics Inc

Heartseed Inc

Help Therapeutics

iHeart Japan Corp

Martin Pharmaceuticals Inc

Olagenesis Corp

Pfizer Inc

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Dilated Cardiomyopathy - Overview

Dilated Cardiomyopathy - Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Products under Development by Companies

Products under Development by Universities/Institutes

Dilated Cardiomyopathy - Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Dilated Cardiomyopathy - Companies Involved in Therapeutics Development

Berlin Cures Holding AG

Bristol-Myers Squibb Co

Celixir Ltd

CellServe GmbH

Dynomics Inc

Heartseed Inc

Help Therapeutics

iHeart Japan Corp

Martin Pharmaceuticals Inc

Olagenesis Corp

Pfizer Inc

Recursion Pharmaceuticals Inc

Renovacor Inc

Shionogi & Co Ltd

Dilated Cardiomyopathy - Drug Profiles

BC-007 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Cell Therapy for Dilated Cardiomyopathy - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

danicamtiv - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

DYN-101 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Gene Therapy to Activate BAG3 for Dilated Cardiomyopathy - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Heartcel - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

HS-001 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

IHJ-301 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

NovoCardia - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

PF-06802861 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

redasemtide trifluoroacetate - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecules for Dilated Cardiomyopathy - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecules for Dilated Cardiomyopathy - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Stem Cell Therapy for Myocardial Infarction and Dilated Cardiomyopathy - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

trimetazidine - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

YS-1402 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Dilated Cardiomyopathy - Dormant Projects

Dilated Cardiomyopathy - Product Development Milestones

Featured News & Press Releases

Sep 09, 2020: MyoKardia doses first patient in phase 2 clinical trial of danicamtiv in genetic dilated cardiomyopathy

Mar 26, 2020: MyoKardia Provides clinical trial update on Danicamtiv study

Oct 28, 2019: MyoKardia Announces Positive MYK-491 Data; Advancing Program into Targeted Genetic Dilated Cardiomyopathy Population

May 30, 2019: MyoKardia’s MYK-491 shows favourable profile in Phase Ia study

Apr 15, 2019: Berlin Cures announces start of Phase IIa for its DNA-based neutralizer of ß1-adrenoceptor autoantibodies

Dec 11, 2018: MyoKardia reports positive data from phase 1b single-ascending dose clinical trial of MYK-491 in dilated cardiomyopathy and systolic heart failure patients

Dec 06, 2018: Berlin Cures steering committee is assembled to facilitate the design and implementation of phase 2 study of BC 007

Oct 30, 2018: MyoKardia Shares Data from new research program ACT-1 at 2018 R&D Day

Feb 26, 2018: Heart Failure Treatment from Berlin Cures Shows Promise in Phase 1 Study

Feb 14, 2018: MyoKardia Begins Patient Dosing in Phase 1b Clinical Study of MYK-491 in Dilated Cardiomyopathy Patients

Nov 02, 2017: MyoKardia Provides Update on MYK-491

Sep 27, 2017: MyoKardia Provides Update on MYK-491 Clinical Progress

Feb 02, 2017: First Subjects Dosed in MyoKardia Phase 1 Study of Dilated Cardiomyopathy Candidate MYK-491

Dec 02, 2016: MyoKardia Announces Receipt of Milestone Payment from Sanofi for DCM Candidate MYK-491

Aug 30, 2016: Array Presents Data from Cardiovascular Trial with ARRY-797 at the European Society of Cardiology Congress

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

List of Tables

List of Tables

Number of Products under Development for Dilated Cardiomyopathy, 2021

Number of Products under Development by Companies, 2021

Number of Products under Development by Universities/Institutes, 2021

Products under Development by Companies, 2021

Products under Development by Universities/Institutes, 2021

Number of Products by Stage and Target, 2021

Number of Products by Stage and Mechanism of Action, 2021

Number of Products by Stage and Route of Administration, 2021

Number of Products by Stage and Molecule Type, 2021

Dilated Cardiomyopathy – Pipeline by Berlin Cures Holding AG, 2021

Dilated Cardiomyopathy – Pipeline by Bristol-Myers Squibb Co, 2021

Dilated Cardiomyopathy – Pipeline by Celixir Ltd, 2021

Dilated Cardiomyopathy – Pipeline by CellServe GmbH, 2021

Dilated Cardiomyopathy – Pipeline by Dynomics Inc, 2021

Dilated Cardiomyopathy – Pipeline by Heartseed Inc, 2021

Dilated Cardiomyopathy – Pipeline by Help Therapeutics, 2021

Dilated Cardiomyopathy – Pipeline by iHeart Japan Corp, 2021

Dilated Cardiomyopathy – Pipeline by Martin Pharmaceuticals Inc, 2021

Dilated Cardiomyopathy – Pipeline by Olagenesis Corp, 2021

Dilated Cardiomyopathy – Pipeline by Pfizer Inc, 2021

Dilated Cardiomyopathy – Pipeline by Recursion Pharmaceuticals Inc, 2021

Dilated Cardiomyopathy – Pipeline by Renovacor Inc, 2021

Dilated Cardiomyopathy – Pipeline by Shionogi & Co Ltd, 2021

Dilated Cardiomyopathy – Dormant Projects, 2021

List of Figures

List of Figures

Number of Products under Development for Dilated Cardiomyopathy, 2021

Number of Products under Development by Companies, 2021

Number of Products by Targets, 2021

Number of Products by Stage and Targets, 2021

Number of Products by Mechanism of Actions, 2021

Number of Products by Stage and Mechanism of Actions, 2021

Number of Products by Routes of Administration, 2021

Number of Products by Stage and Routes of Administration, 2021

Number of Products by Molecule Types, 2021

Number of Products by Stage and Molecule Types, 2021

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