Interleukin 1 (IL1) – Drugs in Development, 2021

According to the recently published report 'Interleukin 1 – Drugs in Development, 2021'; Interleukin 1 (IL1) pipeline Target constitutes close to 36 molecules. Out of which approximately 35 molecules are developed by companies and remaining by the universities/institutes.

Interleukin 1 (IL1) – Interleukin-1 is a cytokine which plays an important role regulation of immune and inflammatory responses. It helps leukocytes pass through blood vessel walls to sites of infection and causes fever by affecting areas of the brain that control body temperature. There are two forms of interleukin-1, alpha and beta. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.

The report 'Interleukin 1 – Drugs in Development, 2021' outlays comprehensive information on the Interleukin 1 (IL1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.

It also reviews key players involved in Interleukin 1 (IL1) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical, Discovery and Unknown stages are 4, 6, 4, 17, 3 and 1 respectively. Similarly, the universities portfolio in Preclinical stages comprises 1 molecules, respectively.

Report covers products from therapy areas Immunology, Oncology, Musculoskeletal Disorders, Cardiovascular, Gastrointestinal, Central Nervous System, Dermatology, Infectious Disease, Genetic Disorders, Metabolic Disorders, Genito Urinary System And Sex Hormones, Hematological Disorders, Respiratory and Ear Nose Throat Disorders which include indications Coronavirus Disease 2019 (COVID-19), Gouty Arthritis (Gout), Inflammation, Non-Small Cell Lung Cancer, Alzheimer's Disease, Atopic Dermatitis (Atopic Eczema), Autoimmune Disorders, Behcet Disease, Colorectal Cancer, Epidermolysis Bullosa, Esophageal Cancer, Familial Mediterranean Fever, Metastatic Melanoma, Muckle-Wells Syndrome, Myocardial Infarction, Pericarditis, Prostate Cancer, Rheumatoid Arthritis, Sickle Cell Disease, Solid Tumor, Squamous Non-Small Cell Lung Cancer, Triple-Negative Breast Cancer (TNBC), Acne Vulgaris, Acute Respiratory Distress Syndrome, Alcoholic Hepatitis, Allergic Rhinitis, Atherosclerosis, Bacterial Cystitis, Bile Duct Cancer (Cholangiocarcinoma), Bladder Cancer, Brain Cancer, Cancer Pain, Cardiovascular Risk Factors, Cervical Cancer, Cholangitis, Crohn's Disease (Regional Enteritis), Diffuse Large B-Cell Lymphoma, Endometrial Cancer, Fallopian Tube Cancer, Familial Cold Autoinflammatory Syndrome (Familial Cold Urticaria), Follicular Lymphoma, Gastric Cancer, Glioblastoma Multiforme (GBM), Head And Neck Cancer, Head And Neck Cancer Squamous Cell Carcinoma, Hearing Disorders, Hemorrhagic Shock, Hidradenitis Suppurativa, Inflammatory Bowel Disease, Inflammatory Pain, Kidney Cancer (Renal Cell Cancer), Kidney Fibrosis, Knee Osteoarthritis, Limited/Distal Colitis, Liver Fibrosis, Lymphoma, Metastatic Breast Cancer, Metastatic Colorectal Cancer, Metastatic Ovarian Cancer, Metastatic Prostate Cancer, Metastatic Renal Cell Carcinoma, Mild Cognitive Impairment, Multiple Myeloma (Kahler Disease), Multiple Sclerosis, Myelodysplastic Syndrome, Neonatal Onset Multisystem Inflammatory Disease, Neuropathic Pain (Neuralgia), Non-Small Cell Lung Carcinoma, Osteoarthritis, Osteosarcoma, Ovarian Cancer, Pancreatic Ductal Adenocarcinoma, Psoriasis, Psoriatic Arthritis, Recurrent Glioblastoma Multiforme (GBM), Renal Cell Carcinoma, Sarcoidosis, Schnitzler Syndrome, Seizures, Soft Tissue Sarcoma, Stroke, Systemic Juvenile Rheumatoid Arthritis, Systemic-Onset Juvenile Idiopathic Arthritis (Still Disease), Transitional Cell Cancer (Urothelial Cell Cancer), Traumatic Brain Injury and Type 2 Diabetes.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

– The report provides a snapshot of the global therapeutic landscape for Interleukin 1 (IL1)

– The report reviews Interleukin 1 (IL1) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources

– The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages

– The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities

– The report reviews key players involved in Interleukin 1 (IL1) targeted therapeutics and enlists all their major and minor projects

– The report assesses Interleukin 1 (IL1) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type

– The report summarizes all the dormant and discontinued pipeline projects

– The report reviews latest news and deals related to Interleukin 1 (IL1) targeted therapeutics

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies

- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

- Identify and understand the targeted therapy areas and indications for Interleukin 1 (IL1)Identify the use of drugs for target identification and drug repurposing

- Identify potential new clients or partners in the target demographic

- Develop strategic initiatives by understanding the focus areas of leading companies

- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics

- Devise corrective measures for pipeline projects by understanding Interleukin 1 (IL1) development landscape

- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Companies mentioned

3SBio Inc

Akeso Inc

Bio-Thera Solutions Ltd

Bioiberica SAU

Devonian Health Group Inc

Flame Biosciences Inc

ImmunoChem Therapeutics LLC

Immunome Inc

Johnson & Johnson

Komipharm International Co Ltd

Link Health Group

Mabpharm Ltd

Medifron DBT Co Ltd

Moderna Inc

Novartis AG

Omnitura Therapeutics Inc

Opsona Therapeutics Ltd

Peptinov SAS

R-Pharm

Regeneron Pharmaceuticals Inc

SelectImmune Pharma AB

Spherium Biomed SL

Swedish Orphan Biovitrum AB

Therapicon Srl

ThioLab LLC

TWi Biotechnology Inc

XBiotech Inc

Table of Contents

Table of Contents

Introduction

Interleukin 1 (IL1) - Overview

Interleukin 1 (IL1) - Therapeutics Development

Interleukin 1 (IL1) - Therapeutics Assessment

Interleukin 1 (IL1) - Companies Involved in Therapeutics Development

Interleukin 1 (IL1) - Drug Profiles

Interleukin 1 (IL1) - Dormant Products

Interleukin 1 (IL1) - Discontinued Products

Interleukin 1 (IL1) - Product Development Milestones

Appendix

List of Tables

List of Tables

Number of Products under Development by Stage of Development, 2021

Number of Products under Development by Therapy Areas, 2021

Number of Products under Development by Indications, 2021

Number of Products under Development by Indications, 2021 (Contd..1)

Number of Products under Development by Indications, 2021 (Contd..2)

Number of Products under Development by Indications, 2021 (Contd..3)

Number of Products under Development by Indications, 2021 (Contd..4)

Number of Products under Development by Companies, 2021

Number of Products under Development by Companies, 2021 (Contd..1)

Products under Development by Companies, 2021

Products under Development by Companies, 2021 (Contd..1)

Products under Development by Companies, 2021 (Contd..2)

Products under Development by Companies, 2021 (Contd..3)

Products under Development by Companies, 2021 (Contd..4)

Products under Development by Companies, 2021 (Contd..5)

Products under Development by Companies, 2021 (Contd..6)

Number of Products under Investigation by Universities/Institutes, 2021

Products under Investigation by Universities/Institutes, 2021

Number of Products by Stage and Mechanism of Actions, 2021

Number of Products by Stage and Route of Administration, 2021

Number of Products by Stage and Molecule Type, 2021

Pipeline by 3SBio Inc, 2021

Pipeline by Akeso Inc, 2021

Pipeline by Bio-Thera Solutions Ltd, 2021

Pipeline by Bioiberica SAU, 2021

Pipeline by Devonian Health Group Inc, 2021

Pipeline by Flame Biosciences Inc, 2021

Pipeline by ImmunoChem Therapeutics LLC, 2021

Pipeline by Immunome Inc, 2021

Pipeline by Johnson & Johnson, 2021

Pipeline by Komipharm International Co Ltd, 2021

Pipeline by Link Health Group, 2021

Pipeline by Mabpharm Ltd, 2021

Pipeline by Medifron DBT Co Ltd, 2021

Pipeline by Moderna Inc, 2021

Pipeline by Novartis AG, 2021

Pipeline by Omnitura Therapeutics Inc, 2021

Pipeline by Opsona Therapeutics Ltd, 2021

Pipeline by Peptinov SAS, 2021

Pipeline by R-Pharm, 2021

Pipeline by Regeneron Pharmaceuticals Inc, 2021

Pipeline by SelectImmune Pharma AB, 2021

Pipeline by Spherium Biomed SL, 2021

Pipeline by Swedish Orphan Biovitrum AB, 2021

Pipeline by Therapicon Srl, 2021

Pipeline by ThioLab LLC, 2021

Pipeline by TWi Biotechnology Inc, 2021

Pipeline by XBiotech Inc, 2021

Dormant Products, 2021

Dormant Products, 2021 (Contd..1)

Dormant Products, 2021 (Contd..2)

Dormant Products, 2021 (Contd..3)

Dormant Products, 2021 (Contd..4)

Dormant Products, 2021 (Contd..5)

Dormant Products, 2021 (Contd..6)

Discontinued Products, 2021

Discontinued Products, 2021 (Contd..1)

Discontinued Products, 2021 (Contd..2)

List of Figures

List of Figures

Number of Products under Development by Stage of Development, 2021

Number of Products under Development by Therapy Areas, 2021

Number of Products under Development by Top 10 Indications, 2021

Number of Products by Mechanism of Actions, 2021

Number of Products by Stage and Mechanism of Actions, 2021

Number of Products by Routes of Administration, 2021

Number of Products by Stage and Routes of Administration, 2021

Number of Products by Molecule Types, 2021

Number of Products by Stage and Molecule Types, 2021

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